| <SPAN style="DISPLAY: inline! important; FLOAT: none; WORD-SPACING: 0px; FONT: 21px/31px 微软雅黑; TEXT-TRANSFORM: none; COLOR: rgb(0,0,0); TEXT-INDENT: 0px; WHITE-SPACE: normal; LETTER-SPACING: normal; BACKGROUND-COLOR: rgb(255,255,255); TEXT-ALIGN: left; orphans: 2; widows: 2; webkit-text-size-adjust: auto; webkit-text-stroke-width: 0px">
<P style="BORDER-TOP-WIDTH: 0px; PADDING-RIGHT: 0px; PADDING-LEFT: 0px; BORDER-LEFT-WIDTH: 0px; BORDER-BOTTOM-WIDTH: 0px; PADDING-BOTTOM: 0px; MARGIN: 0cm 0cm 0pt; WORD-SPACING: 0px; FONT: 14px/21px simsun; TEXT-TRANSFORM: none; COLOR: rgb(85,85,85); WORD-BREAK: normal; TEXT-INDENT: 24pt; PADDING-TOP: 0px; WHITE-SPACE: normal; LIST-STYLE-TYPE: none; LETTER-SPACING: normal; BACKGROUND-COLOR: white; TEXT-ALIGN: left; BORDER-RIGHT-WIDTH: 0px; WORD-WRAP: normal; orphans: 2; widows: 2; webkit-text-size-adjust: auto; webkit-text-stroke-width: 0px; border-image: initial; background-origin: initial; background-clip: initial" align=left><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">据哈佛医学院</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">Beth Israel Deaconess</SPAN><FONT size=3><SPAN class=Apple-converted-space><FONT color=#555555> </FONT></SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">医学中心研究人员报道：对有抑郁症，并试图怀孕的妇女处方一类被称为选择性</SPAN></FONT><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">5-</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">羟色胺再摄取抑制剂（</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">SSRIs</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">）的抗抑郁药必须非常谨慎，之前应该作充分咨询，这是由于这类药物使流产、早产，新生儿、健康并发症和包括孤独症等可能的长期神经行为异常的风险增加。</SPAN></P>
<P style="BORDER-TOP-WIDTH: 0px; PADDING-RIGHT: 0px; PADDING-LEFT: 0px; BORDER-LEFT-WIDTH: 0px; BORDER-BOTTOM-WIDTH: 0px; PADDING-BOTTOM: 0px; MARGIN: 0cm 0cm 0pt; WORD-SPACING: 0px; FONT: 14px/21px simsun; TEXT-TRANSFORM: none; COLOR: rgb(85,85,85); WORD-BREAK: normal; TEXT-INDENT: 24pt; PADDING-TOP: 0px; WHITE-SPACE: normal; LIST-STYLE-TYPE: none; LETTER-SPACING: normal; BACKGROUND-COLOR: white; TEXT-ALIGN: left; BORDER-RIGHT-WIDTH: 0px; WORD-WRAP: normal; orphans: 2; widows: 2; webkit-text-size-adjust: auto; webkit-text-stroke-width: 0px; border-image: initial; background-origin: initial; background-clip: initial" align=left><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">“抑郁症和不孕不育是互不相干的两种病症，没有明确的治疗指南。”报告的主要作者，医学中心产科、妇科和生殖生物学助理临床教授，心智</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">/</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">体魄健康中心执行主任</SPAN><SPAN lang=EN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN">Alice Domar</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">指出。作者试图为妇女患者和医护人员决策提供有用的分析数据。</SPAN></P>
<P style="BORDER-TOP-WIDTH: 0px; PADDING-RIGHT: 0px; PADDING-LEFT: 0px; BORDER-LEFT-WIDTH: 0px; BORDER-BOTTOM-WIDTH: 0px; PADDING-BOTTOM: 0px; MARGIN: 0cm 0cm 0pt; WORD-SPACING: 0px; FONT: 14px/21px simsun; TEXT-TRANSFORM: none; COLOR: rgb(85,85,85); WORD-BREAK: normal; TEXT-INDENT: 24pt; PADDING-TOP: 0px; WHITE-SPACE: normal; LIST-STYLE-TYPE: none; LETTER-SPACING: normal; BACKGROUND-COLOR: white; TEXT-ALIGN: left; BORDER-RIGHT-WIDTH: 0px; WORD-WRAP: normal; orphans: 2; widows: 2; webkit-text-size-adjust: auto; webkit-text-stroke-width: 0px; border-image: initial; background-origin: initial; background-clip: initial" align=left><SPAN lang=EN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN">Domar</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">与来自</SPAN><SPAN lang=EN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN">Tufts</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">和</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">MetroWest</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">两家医学中心的同事对评价服用抗抑郁药物期间怀孕妇女已经发表的研究资料进行了一项综合调查分析。写成的这篇综述刊登在《人类生殖》（</SPAN><I><SPAN lang=EN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN">Human Reproduction</SPAN></I><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">）杂志</SPAN><FONT size=3><SPAN class=Apple-converted-space><FONT color=#555555> </FONT></SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">10</SPAN></FONT><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">月</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">31</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">日</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">网络版上。</SPAN></P>
<P style="BORDER-TOP-WIDTH: 0px; PADDING-RIGHT: 0px; PADDING-LEFT: 0px; BORDER-LEFT-WIDTH: 0px; BORDER-BOTTOM-WIDTH: 0px; PADDING-BOTTOM: 0px; MARGIN: 0cm 0cm 0pt; WORD-SPACING: 0px; FONT: 14px/21px simsun; TEXT-TRANSFORM: none; COLOR: rgb(85,85,85); WORD-BREAK: normal; TEXT-INDENT: 24pt; PADDING-TOP: 0px; WHITE-SPACE: normal; LIST-STYLE-TYPE: none; LETTER-SPACING: normal; BACKGROUND-COLOR: white; TEXT-ALIGN: left; BORDER-RIGHT-WIDTH: 0px; WORD-WRAP: normal; orphans: 2; widows: 2; webkit-text-size-adjust: auto; webkit-text-stroke-width: 0px; border-image: initial; background-origin: initial; background-clip: initial" align=left><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">MetroWest</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">医学中心产科和妇科主任、</SPAN><SPAN lang=EN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN">Tufts</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">医学中心母胎医学专家，</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">资深作者</SPAN><SPAN lang=EN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN">Adam Urato</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">指出：</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">这篇综述</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">有三个要点</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">。他表示“首先，使用</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">SSRI</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">类抗抑郁药导致不良妊娠结果的风险有明确的证据；其二，没有证据表明这些药物会对母亲和婴儿产生有益作用；第三，我们强烈地感到，患者、医务人员和公众需要充分了解这些信息。”</SPAN></P>
<P style="BORDER-TOP-WIDTH: 0px; PADDING-RIGHT: 0px; PADDING-LEFT: 0px; BORDER-LEFT-WIDTH: 0px; BORDER-BOTTOM-WIDTH: 0px; PADDING-BOTTOM: 0px; MARGIN: 0cm 0cm 0pt; WORD-SPACING: 0px; FONT: 14px/21px simsun; TEXT-TRANSFORM: none; COLOR: rgb(85,85,85); WORD-BREAK: normal; TEXT-INDENT: 24pt; PADDING-TOP: 0px; WHITE-SPACE: normal; LIST-STYLE-TYPE: none; LETTER-SPACING: normal; BACKGROUND-COLOR: white; TEXT-ALIGN: left; BORDER-RIGHT-WIDTH: 0px; WORD-WRAP: normal; orphans: 2; widows: 2; webkit-text-size-adjust: auto; webkit-text-stroke-width: 0px; border-image: initial; background-origin: initial; background-clip: initial" align=left><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">在过去的</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">20</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">年中，抗抑郁药的使用增加了</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">4</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">倍。在美国，抗抑郁药在</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">18</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">岁至</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">44</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">岁年龄段人群属于最常用的处方药，而对大多数女性正是生育年龄，并且这一年龄段妇女更容易不孕不育。</SPAN></P>
<P style="BORDER-TOP-WIDTH: 0px; PADDING-RIGHT: 0px; PADDING-LEFT: 0px; BORDER-LEFT-WIDTH: 0px; BORDER-BOTTOM-WIDTH: 0px; PADDING-BOTTOM: 0px; MARGIN: 0cm 0cm 0pt; WORD-SPACING: 0px; FONT: 14px/21px simsun; TEXT-TRANSFORM: none; COLOR: rgb(85,85,85); WORD-BREAK: normal; TEXT-INDENT: 24pt; PADDING-TOP: 0px; WHITE-SPACE: normal; LIST-STYLE-TYPE: none; LETTER-SPACING: normal; BACKGROUND-COLOR: white; TEXT-ALIGN: left; BORDER-RIGHT-WIDTH: 0px; WORD-WRAP: normal; orphans: 2; widows: 2; webkit-text-size-adjust: auto; webkit-text-stroke-width: 0px; border-image: initial; background-origin: initial; background-clip: initial" align=left><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">作者在报告中称：“据美国疾病预防控制中心数据，每年出生的婴儿超过</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">1</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">％为试管婴儿，多数妇女会在不孕症治疗期间出现抑郁症，特别是受孕未获成功情况下。”</SPAN></P>
<P style="BORDER-TOP-WIDTH: 0px; PADDING-RIGHT: 0px; PADDING-LEFT: 0px; BORDER-LEFT-WIDTH: 0px; BORDER-BOTTOM-WIDTH: 0px; PADDING-BOTTOM: 0px; MARGIN: 0cm 0cm 0pt; WORD-SPACING: 0px; FONT: 14px/21px simsun; TEXT-TRANSFORM: none; COLOR: rgb(85,85,85); WORD-BREAK: normal; TEXT-INDENT: 24pt; PADDING-TOP: 0px; WHITE-SPACE: normal; LIST-STYLE-TYPE: none; LETTER-SPACING: normal; BACKGROUND-COLOR: white; TEXT-ALIGN: left; BORDER-RIGHT-WIDTH: 0px; WORD-WRAP: normal; orphans: 2; widows: 2; webkit-text-size-adjust: auto; webkit-text-stroke-width: 0px; border-image: initial; background-origin: initial; background-clip: initial" align=left><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">有多达</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">11</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">％妇女会服用</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">SSRI</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">控制抑郁症状，但</SPAN><SPAN lang=EN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN">Domar</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">和他的同事们发现，服用抗抑郁药没有使妊娠改善的证据，而事实恰恰相反。他们读到了大量围绕</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">SSRI</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">疗效的争议。许多研究发现，</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">SSRI</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">类药物对抑郁症相比安慰剂没有或只是稍有效果。</SPAN></P>
<P style="BORDER-TOP-WIDTH: 0px; PADDING-RIGHT: 0px; PADDING-LEFT: 0px; BORDER-LEFT-WIDTH: 0px; BORDER-BOTTOM-WIDTH: 0px; PADDING-BOTTOM: 0px; MARGIN: 0cm 0cm 0pt; WORD-SPACING: 0px; FONT: 14px/21px simsun; TEXT-TRANSFORM: none; COLOR: rgb(85,85,85); WORD-BREAK: normal; TEXT-INDENT: 24pt; PADDING-TOP: 0px; WHITE-SPACE: normal; LIST-STYLE-TYPE: none; LETTER-SPACING: normal; BACKGROUND-COLOR: white; TEXT-ALIGN: left; BORDER-RIGHT-WIDTH: 0px; WORD-WRAP: normal; orphans: 2; widows: 2; webkit-text-size-adjust: auto; webkit-text-stroke-width: 0px; border-image: initial; background-origin: initial; background-clip: initial" align=left><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">“从更广泛意义上说，给绝大多数育龄妇女处方的抗抑郁药几无有益的证据，而风险的证据倒是相当充足，”作者写道。</SPAN></P>
<P style="BORDER-TOP-WIDTH: 0px; PADDING-RIGHT: 0px; PADDING-LEFT: 0px; BORDER-LEFT-WIDTH: 0px; BORDER-BOTTOM-WIDTH: 0px; PADDING-BOTTOM: 0px; MARGIN: 0cm 0cm 0pt; WORD-SPACING: 0px; FONT: 14px/21px simsun; TEXT-TRANSFORM: none; COLOR: rgb(85,85,85); WORD-BREAK: normal; TEXT-INDENT: 24pt; PADDING-TOP: 0px; WHITE-SPACE: normal; LIST-STYLE-TYPE: none; LETTER-SPACING: normal; BACKGROUND-COLOR: white; TEXT-ALIGN: left; BORDER-RIGHT-WIDTH: 0px; WORD-WRAP: normal; orphans: 2; widows: 2; webkit-text-size-adjust: auto; webkit-text-stroke-width: 0px; border-image: initial; background-origin: initial; background-clip: initial" align=left><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">有越来越多的证据表明，对于初始服用者而言</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">SSRI</SPAN><SPAN lang=EN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN">s</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">可降低接受生育治疗妇女的怀孕率。此外，一些研究始终显示，使用</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">SSRI</SPAN><SPAN lang=EN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN">s</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">的妇女流产率上升。还有一个先天发育异常的强烈信号，最引人注目的是使用抗抑郁药</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">Paxil</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">（</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">p</SPAN><SPAN lang=EN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN">aroxetine</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">，帕罗西汀</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">）与心脏缺陷有关联。</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US"><BR><FONT style="WORD-BREAK: normal; LINE-HEIGHT: 24px; WORD-WRAP: normal"><FONT size=3><FONT face=Arial><SPAN style="WORD-BREAK: normal; LINE-HEIGHT: 24px; WORD-WRAP: normal"><WBR><WBR><WBR></SPAN><SPAN class=Apple-converted-space></SPAN>2005</FONT></FONT></FONT></SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">年，</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">FDA</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">要求帕罗西汀的制造商葛兰素史克将帕罗西汀的妊娠风险等级由</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">C</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">改为</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">D</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">，</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">D</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">级即表示对胎儿有风险。</SPAN></P>
<P style="BORDER-TOP-WIDTH: 0px; PADDING-RIGHT: 0px; PADDING-LEFT: 0px; BORDER-LEFT-WIDTH: 0px; BORDER-BOTTOM-WIDTH: 0px; PADDING-BOTTOM: 0px; MARGIN: 0cm 0cm 0pt; WORD-SPACING: 0px; FONT: 14px/21px simsun; TEXT-TRANSFORM: none; COLOR: rgb(85,85,85); WORD-BREAK: normal; TEXT-INDENT: 24pt; PADDING-TOP: 0px; WHITE-SPACE: normal; LIST-STYLE-TYPE: none; LETTER-SPACING: normal; BACKGROUND-COLOR: white; TEXT-ALIGN: left; BORDER-RIGHT-WIDTH: 0px; WORD-WRAP: normal; orphans: 2; widows: 2; webkit-text-size-adjust: auto; webkit-text-stroke-width: 0px; border-image: initial; background-origin: initial; background-clip: initial" align=left><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">“早产也许是最紧急的产科并发症，在超过</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">30</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">项研究中有压倒性的证据显示服用抗抑郁药的妇女早产风险增加，”作者写道。</SPAN></P>
<P style="BORDER-TOP-WIDTH: 0px; PADDING-RIGHT: 0px; PADDING-LEFT: 0px; BORDER-LEFT-WIDTH: 0px; BORDER-BOTTOM-WIDTH: 0px; PADDING-BOTTOM: 0px; MARGIN: 0cm 0cm 0pt; WORD-SPACING: 0px; FONT: 14px/21px simsun; TEXT-TRANSFORM: none; COLOR: rgb(85,85,85); WORD-BREAK: normal; TEXT-INDENT: 24pt; PADDING-TOP: 0px; WHITE-SPACE: normal; LIST-STYLE-TYPE: none; LETTER-SPACING: normal; BACKGROUND-COLOR: white; TEXT-ALIGN: left; BORDER-RIGHT-WIDTH: 0px; WORD-WRAP: normal; orphans: 2; widows: 2; webkit-text-size-adjust: auto; webkit-text-stroke-width: 0px; border-image: initial; background-origin: initial; background-clip: initial" align=left><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">“这是一个重大的发现，我们知道，</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">37</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">周前出生的婴儿存在许多短期和长期的健康问题风险，早产儿护理的医疗保健支出达数十亿美元。”</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">Urato</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">说。</SPAN></P>
<P style="BORDER-TOP-WIDTH: 0px; PADDING-RIGHT: 0px; PADDING-LEFT: 0px; BORDER-LEFT-WIDTH: 0px; BORDER-BOTTOM-WIDTH: 0px; PADDING-BOTTOM: 0px; MARGIN: 0cm 0cm 0pt; WORD-SPACING: 0px; FONT: 14px/21px simsun; TEXT-TRANSFORM: none; COLOR: rgb(85,85,85); WORD-BREAK: normal; TEXT-INDENT: 24pt; PADDING-TOP: 0px; WHITE-SPACE: normal; LIST-STYLE-TYPE: none; LETTER-SPACING: normal; BACKGROUND-COLOR: white; TEXT-ALIGN: left; BORDER-RIGHT-WIDTH: 0px; WORD-WRAP: normal; orphans: 2; widows: 2; webkit-text-size-adjust: auto; webkit-text-stroke-width: 0px; border-image: initial; background-origin: initial; background-clip: initial" align=left><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">现有的数据还表明，使用抗抑郁药，尤其是如果它覆盖受孕头三个月，会导致妊娠高血压和先兆子痫风险增加。</SPAN></P>
<P style="BORDER-TOP-WIDTH: 0px; PADDING-RIGHT: 0px; PADDING-LEFT: 0px; BORDER-LEFT-WIDTH: 0px; BORDER-BOTTOM-WIDTH: 0px; PADDING-BOTTOM: 0px; MARGIN: 0cm 0cm 0pt; WORD-SPACING: 0px; FONT: 14px/21px simsun; TEXT-TRANSFORM: none; COLOR: rgb(85,85,85); WORD-BREAK: normal; TEXT-INDENT: 24pt; PADDING-TOP: 0px; WHITE-SPACE: normal; LIST-STYLE-TYPE: none; LETTER-SPACING: normal; BACKGROUND-COLOR: white; TEXT-ALIGN: left; BORDER-RIGHT-WIDTH: 0px; WORD-WRAP: normal; orphans: 2; widows: 2; webkit-text-size-adjust: auto; webkit-text-stroke-width: 0px; border-image: initial; background-origin: initial; background-clip: initial" align=left><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">作者提出：“鉴于高血压在孕产妇和新生儿发病率和死亡率的重要影响，以及抗抑郁药使用如此广泛，必须在这方面作进一步研究。”</SPAN></P>
<P style="BORDER-TOP-WIDTH: 0px; PADDING-RIGHT: 0px; PADDING-LEFT: 0px; BORDER-LEFT-WIDTH: 0px; BORDER-BOTTOM-WIDTH: 0px; PADDING-BOTTOM: 0px; MARGIN: 0cm 0cm 0pt; WORD-SPACING: 0px; FONT: 14px/21px simsun; TEXT-TRANSFORM: none; COLOR: rgb(85,85,85); WORD-BREAK: normal; TEXT-INDENT: 24pt; PADDING-TOP: 0px; WHITE-SPACE: normal; LIST-STYLE-TYPE: none; LETTER-SPACING: normal; BACKGROUND-COLOR: white; TEXT-ALIGN: left; BORDER-RIGHT-WIDTH: 0px; WORD-WRAP: normal; orphans: 2; widows: 2; webkit-text-size-adjust: auto; webkit-text-stroke-width: 0px; border-image: initial; background-origin: initial; background-clip: initial" align=left><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">长期服用</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">SSRIs</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">还会导致出生体重降低</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">10%</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">的发生率，并且呼吸窘迫症发生率率增加。</SPAN></P>
<P style="BORDER-TOP-WIDTH: 0px; PADDING-RIGHT: 0px; PADDING-LEFT: 0px; BORDER-LEFT-WIDTH: 0px; BORDER-BOTTOM-WIDTH: 0px; PADDING-BOTTOM: 0px; MARGIN: 0cm 0cm 0pt; WORD-SPACING: 0px; FONT: 14px/21px simsun; TEXT-TRANSFORM: none; COLOR: rgb(85,85,85); WORD-BREAK: normal; TEXT-INDENT: 24pt; PADDING-TOP: 0px; WHITE-SPACE: normal; LIST-STYLE-TYPE: none; LETTER-SPACING: normal; BACKGROUND-COLOR: white; TEXT-ALIGN: left; BORDER-RIGHT-WIDTH: 0px; WORD-WRAP: normal; orphans: 2; widows: 2; webkit-text-size-adjust: auto; webkit-text-stroke-width: 0px; border-image: initial; background-origin: initial; background-clip: initial" align=left><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">与服用抗抑郁药相关的健康并发症还会影响到婴幼儿。</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">2006</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">年的一项研究显示，子宫内婴儿暴露于抗抑郁药出现新生儿行为综合征风险增加</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">30</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">％，最常见的有持续性哭闹、神经过敏和喂饲困难。较少情况下会导致癫痫发作、呼吸困难，乃至需要气管插管。</SPAN></P>
<P style="BORDER-TOP-WIDTH: 0px; PADDING-RIGHT: 0px; PADDING-LEFT: 0px; BORDER-LEFT-WIDTH: 0px; BORDER-BOTTOM-WIDTH: 0px; PADDING-BOTTOM: 0px; MARGIN: 0cm 0cm 0pt; WORD-SPACING: 0px; FONT: 14px/21px simsun; TEXT-TRANSFORM: none; COLOR: rgb(85,85,85); WORD-BREAK: normal; TEXT-INDENT: 24pt; PADDING-TOP: 0px; WHITE-SPACE: normal; LIST-STYLE-TYPE: none; LETTER-SPACING: normal; BACKGROUND-COLOR: white; TEXT-ALIGN: left; BORDER-RIGHT-WIDTH: 0px; WORD-WRAP: normal; orphans: 2; widows: 2; webkit-text-size-adjust: auto; webkit-text-stroke-width: 0px; border-image: initial; background-origin: initial; background-clip: initial" align=left><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">一些研究还表明，在婴儿和幼儿行动发育延迟。一项</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">Kaiser Permanente</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">研究显示：“妊娠期间服用</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">SSRIs</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">的<FONT size=3><SPAN style="WORD-BREAK: normal; LINE-HEIGHT: 24px; WORD-WRAP: normal">产妇</SPAN>，子女</FONT></SPAN><FONT style="WORD-BREAK: normal; LINE-HEIGHT: 24px; WORD-WRAP: normal"><FONT style="WORD-BREAK: normal; LINE-HEIGHT: 24px; WORD-WRAP: normal" face="Times New Roman" size=3>自闭症谱系障碍风险增加</FONT></FONT><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">2</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">倍，在怀孕头三个月以治疗</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">SSRIs</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">副作用最强。”</SPAN></P>
<P style="BORDER-TOP-WIDTH: 0px; PADDING-RIGHT: 0px; PADDING-LEFT: 0px; BORDER-LEFT-WIDTH: 0px; BORDER-BOTTOM-WIDTH: 0px; PADDING-BOTTOM: 0px; MARGIN: 0cm 0cm 0pt; WORD-SPACING: 0px; FONT: 14px/21px simsun; TEXT-TRANSFORM: none; COLOR: rgb(85,85,85); WORD-BREAK: normal; TEXT-INDENT: 24pt; PADDING-TOP: 0px; WHITE-SPACE: normal; LIST-STYLE-TYPE: none; LETTER-SPACING: normal; BACKGROUND-COLOR: white; TEXT-ALIGN: left; BORDER-RIGHT-WIDTH: 0px; WORD-WRAP: normal; orphans: 2; widows: 2; webkit-text-size-adjust: auto; webkit-text-stroke-width: 0px; border-image: initial; background-origin: initial; background-clip: initial" align=left><SPAN lang=EN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN">Domar</SPAN><FONT size=3><SPAN class=Apple-converted-space><FONT color=#555555> </FONT></SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">提醒：“有足够证据强烈建议对怀孕或正试图怀孕妇女处方</SPAN></FONT><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">SSRIs</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">必须非常谨慎。强调抑郁症应该认真对待，可以考虑其它与</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">SSRIs</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">同样有效，甚至更为有效的而无上述风险的治疗选择。”</SPAN></P>
<P style="BORDER-TOP-WIDTH: 0px; PADDING-RIGHT: 0px; PADDING-LEFT: 0px; BORDER-LEFT-WIDTH: 0px; BORDER-BOTTOM-WIDTH: 0px; PADDING-BOTTOM: 0px; MARGIN: 0cm 0cm 0pt; WORD-SPACING: 0px; FONT: 14px/21px simsun; TEXT-TRANSFORM: none; COLOR: rgb(85,85,85); WORD-BREAK: normal; TEXT-INDENT: 24pt; PADDING-TOP: 0px; WHITE-SPACE: normal; LIST-STYLE-TYPE: none; LETTER-SPACING: normal; BACKGROUND-COLOR: white; TEXT-ALIGN: left; BORDER-RIGHT-WIDTH: 0px; WORD-WRAP: normal; orphans: 2; widows: 2; webkit-text-size-adjust: auto; webkit-text-stroke-width: 0px; border-image: initial; background-origin: initial; background-clip: initial" align=left><SPAN lang=EN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN">Domar</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">审视了评估</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">普通抑郁症人群中</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">不同</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">治疗方式的各项研究结果，包括心理治疗、运动、放松训练、瑜伽、针灸和营养补充剂。虽然许多选择能够获得某些益处，心理治疗，特别是认知行为疗法（</SPAN><SPAN lang=EN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN">CBT</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">）最有希望的。</SPAN></P>
<P style="BORDER-TOP-WIDTH: 0px; PADDING-RIGHT: 0px; PADDING-LEFT: 0px; BORDER-LEFT-WIDTH: 0px; BORDER-BOTTOM-WIDTH: 0px; PADDING-BOTTOM: 0px; MARGIN: 0cm 0cm 0pt; WORD-SPACING: 0px; FONT: 14px/21px simsun; TEXT-TRANSFORM: none; COLOR: rgb(85,85,85); WORD-BREAK: normal; TEXT-INDENT: 24pt; PADDING-TOP: 0px; WHITE-SPACE: normal; LIST-STYLE-TYPE: none; LETTER-SPACING: normal; BACKGROUND-COLOR: white; TEXT-ALIGN: left; BORDER-RIGHT-WIDTH: 0px; WORD-WRAP: normal; orphans: 2; widows: 2; webkit-text-size-adjust: auto; webkit-text-stroke-width: 0px; border-image: initial; background-origin: initial; background-clip: initial" align=left><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">“治疗中重度抑郁症，</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">CBT</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">的效果相当于抗抑郁药，最近的研究表明，它对重度抑郁症治疗也是有效的，”作者指出。</SPAN></P>
<P style="BORDER-TOP-WIDTH: 0px; PADDING-RIGHT: 0px; PADDING-LEFT: 0px; BORDER-LEFT-WIDTH: 0px; BORDER-BOTTOM-WIDTH: 0px; PADDING-BOTTOM: 0px; MARGIN: 0cm 0cm 0pt; WORD-SPACING: 0px; FONT: 14px/21px simsun; TEXT-TRANSFORM: none; COLOR: rgb(85,85,85); WORD-BREAK: normal; TEXT-INDENT: 24pt; PADDING-TOP: 0px; WHITE-SPACE: normal; LIST-STYLE-TYPE: none; LETTER-SPACING: normal; BACKGROUND-COLOR: white; TEXT-ALIGN: left; BORDER-RIGHT-WIDTH: 0px; WORD-WRAP: normal; orphans: 2; widows: 2; webkit-text-size-adjust: auto; webkit-text-stroke-width: 0px; border-image: initial; background-origin: initial; background-clip: initial" align=left><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">2008</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">年一项研究表明，接受治疗不孕不育治疗的抑郁症妇女</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">CBT</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">的结果令人印象深刻。接受</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">CBT</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">的妇女</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">79</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">％症状明显减轻，相比之下用药组妇女仅</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">50</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">％达到同样效果。</SPAN></P>
<P style="BORDER-TOP-WIDTH: 0px; PADDING-RIGHT: 0px; PADDING-LEFT: 0px; BORDER-LEFT-WIDTH: 0px; BORDER-BOTTOM-WIDTH: 0px; PADDING-BOTTOM: 0px; MARGIN: 0cm 0cm 0pt; WORD-SPACING: 0px; FONT: 14px/21px simsun; TEXT-TRANSFORM: none; COLOR: rgb(85,85,85); WORD-BREAK: normal; TEXT-INDENT: 24pt; PADDING-TOP: 0px; WHITE-SPACE: normal; LIST-STYLE-TYPE: none; LETTER-SPACING: normal; BACKGROUND-COLOR: white; TEXT-ALIGN: left; BORDER-RIGHT-WIDTH: 0px; WORD-WRAP: normal; orphans: 2; widows: 2; webkit-text-size-adjust: auto; webkit-text-stroke-width: 0px; border-image: initial; background-origin: initial; background-clip: initial" align=left><SPAN lang=EN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN">Domar</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">总结说：</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">“不过，这些替代治疗选择可能不适合所有患者，服用抗抑郁药而考虑怀孕的妇女应该与医师就继续服药的风险和效益进行认真讨论，因为没有数据表明在怀孕的这个时间点服用一种</SPAN><SPAN lang=EN-US style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: Arial; WORD-WRAP: normal" xml:lang="EN-US">SSRI</SPAN><SPAN style="FONT-SIZE: 12pt; COLOR: black; WORD-BREAK: normal; LINE-HEIGHT: 24px; FONT-FAMILY: 宋体; WORD-WRAP: normal">有好处，我们的研究所有结论均表明风险增加。”</SPAN></P></SPAN> |
