| <P class=headmargintop3padadj0 style="MARGIN: 0cm 0cm 0pt"><SPAN lang=EN-US style="COLOR: black; FONT-FAMILY: Arial"><?xml:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" /><o:p></o:p></SPAN> </P>
<P><SPAN style="COLOR: black; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial">挪威的一项研究发现，采用一种纳曲酮植入剂可显著降低海洛因依赖性，这对海洛因依赖患者的治疗选择有重要意义。</SPAN><SPAN lang=EN-US style="COLOR: black; FONT-FAMILY: Arial"><o:p></o:p></SPAN></P>
<P><SPAN style="COLOR: black; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial">目前，美沙酮或</SPAN><SPAN lang=EN-US style="COLOR: black; FONT-FAMILY: Arial">Subutex</SPAN><SPAN style="COLOR: black; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial">是治疗海洛因依赖的最常见方法，这些物质类似吗啡具有成瘾性，但可以减少患者海洛因的使用和犯罪行为。</SPAN><SPAN lang=EN-US style="COLOR: black; FONT-FAMILY: Arial"><o:p></o:p></SPAN></P>
<P><SPAN style="COLOR: black; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial">该研究纳入了</SPAN><SPAN lang=EN-US style="COLOR: black; FONT-FAMILY: Arial">56</SPAN><SPAN style="COLOR: black; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial">名海洛因依赖患者，他们都经历过戒毒治疗并希望戒除海洛因成瘾性。一半的受试者皮下埋置</SPAN><SPAN lang=EN-US style="COLOR: black; FONT-FAMILY: Arial">20</SPAN><SPAN style="COLOR: black; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial">粒含纳曲酮的胶囊，其可从盐水溶液中逐渐释放以产生为期</SPAN><SPAN lang=EN-US style="COLOR: black; FONT-FAMILY: Arial">6</SPAN><SPAN style="COLOR: black; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial">个月的阻断效应。</SPAN><SPAN lang=EN-US style="COLOR: black; FONT-FAMILY: Arial"><o:p></o:p></SPAN></P>
<P><SPAN lang=EN-US style="COLOR: black; FONT-FAMILY: Arial">6</SPAN><SPAN style="COLOR: black; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial">个月后发现，纳曲酮组患者避免使用海洛因和吗啡等物质的人数是对照组的两倍多。那些接受纳曲酮但未设法终止使用海洛因的患者，与他们开始治疗时相比，海洛因的使用量减少了一半以上。而对照组中大多数患者复吸（每日使用海洛因）。</SPAN><SPAN lang=EN-US style="COLOR: black; FONT-FAMILY: Arial"><o:p></o:p></SPAN></P>
<P><SPAN style="COLOR: black; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial">此外，受试者对纳曲酮植入剂的治疗满意度很高，在从</SPAN><SPAN lang=EN-US style="COLOR: black; FONT-FAMILY: Arial">0</SPAN><SPAN style="COLOR: black; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial">到</SPAN><SPAN lang=EN-US style="COLOR: black; FONT-FAMILY: Arial">100</SPAN><SPAN style="COLOR: black; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial">的评分级别中为该胶囊评</SPAN><SPAN lang=EN-US style="COLOR: black; FONT-FAMILY: Arial">85</SPAN><SPAN style="COLOR: black; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial">分。</SPAN><SPAN lang=EN-US style="COLOR: black; FONT-FAMILY: Arial"><o:p></o:p></SPAN></P>
<P><SPAN style="COLOR: black; mso-ascii-font-family: Arial; mso-hansi-font-family: Arial">尽管这是一个规模较小的研究，但却有望为那些药物滥用者提供一种新的治疗选择。</SPAN><SPAN lang=EN-US style="COLOR: black; FONT-FAMILY: Arial"><o:p></o:p></SPAN></P>
<P><SPAN lang=EN-US style="COLOR: black; FONT-FAMILY: Arial"><o:p> </o:p></SPAN></P> |
